应用激光, 2004, 24 (2): 112, 网络出版: 2006-05-10
肝硬化的血清荧光光谱诊断研究
Diagnosis of Hepatocirrhosis by Fluorescence Spectrum of Serum
摘要
本文采用 4 76 .5nm的氩离子激发光激发肝硬化患者及健康人血清样品的自体荧光 ,分析了 4 90 - 6 0 0nm范围内的荧光光谱 ,发现二者光谱的带宽和相对强度比I4 90 /I6 0 0存在明显差异 ,同时使用这两个参量对样品进行分析时 ,与病理结果相比较得到了 76 .5 %的总符合率 ,该结果对肝硬化的光谱诊断有一定的参考价值
Abstract
Laser-induced auto-fluorescence spectra of healthy and hepatocirrhosis serum at the excitation of Argon laser (4.76nm) were collected.The fluorescence spectra were analyzed from 490nm to 600nm.Distinct difference of bandwidth and ratio of intensity (1490?1600)of spectra between healthy and hepatocirrhosis serum are found.When two parameters were used at the same tine,consistent degree was 76.5% between experimental and pathological results.
李建东, 丁建华, 吴敏, 秦少平, 司希俭, 赵钢. 肝硬化的血清荧光光谱诊断研究[J]. 应用激光, 2004, 24(2): 112. 李建东, 丁建华, 吴敏, 秦少平, 司希俭, 赵钢. Diagnosis of Hepatocirrhosis by Fluorescence Spectrum of Serum[J]. APPLIED LASER, 2004, 24(2): 112.
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