激光生物学报, 2003, 12 (3): 187, 网络出版: 2006-06-01
紫光激发中药光敏剂用于早期胃癌的诊断
Stimulation of Violet Lasers to Traditional Chinese Medicine Photosensitizer for Diagnosis of Early-stage Gastric Cancer
摘要
采用405nm紫光激发传统中药光敏剂(CpD4)发射的荧光中心波长在660nm.红色荧光能深入组织,因而能够应用在胃癌早期诊断及治疗中.本文测定了中药光敏剂的吸收光谱和发射荧光光谱,并提出了二种用于激发光敏剂的紫光光源.一种为"Hg-Xe"灯,发射峰为433nm;另一种为采用紫光LD,发射峰为405nm.这二种波长和中药光敏剂的吸收峰完全匹配.
Abstract
The traditional Chinese medicine photosensitizer (CpD4) gives off the red fluorescence at a central wavelength 660nm under the stimulation of the violet laser at 405nm. The red fluorescence can penetrate into the tissues deeply, not only in the diagnostic test, but in the treatment as well. The characteristic absorption spectrum and fluorescence emission spectrum of the traditional Chinese medicine photosensitizer are measured, and two violet light sources matching with the spectrums are proposed as well. One is "HgXe" lamp with a special configuration at 433nm at the peak power, and the other is violet LD with a wavelength 405nm at the peak power, which exactly matches the absorption peak of the traditional Chinese medicine photosensitizer.
马养武, 李建平, 厉兰娜. 紫光激发中药光敏剂用于早期胃癌的诊断[J]. 激光生物学报, 2003, 12(3): 187. 马养武, 李建平, 厉兰娜. Stimulation of Violet Lasers to Traditional Chinese Medicine Photosensitizer for Diagnosis of Early-stage Gastric Cancer[J]. Acta Laser Biology Sinica, 2003, 12(3): 187.