激光生物学报, 2004, 13 (3): 194, 网络出版: 2006-06-11
视网膜单细胞成像技术研究
Single Cell Imaging of the Living Human Retina
自适应光学 视网膜 像差 变形镜 Shack-hartman波前像差传感器 adaptive optics retina aberration deformable mirror Shack-hartman wavefront sensor
摘要
建立了一台基于37单元变形镜、Shack-hartman波前像差传感器和12位科研级CCD相机的自适应光学视网膜相机.采用一个中心波长为679nm的超辐射二极管(SLD)作为相机的光源,通过将超辐射二极管和多模光纤耦合,显著减小了SLD光源的空间相干性,从而消除了散斑噪声对成像的影响.多模光纤的输出提供了一种高亮度、均匀照明的光源,使人眼视网膜单细胞成像的速度达到4.8幅/秒.
Abstract
An adaptive optics(AO) retina camera that is based on a 37 actuator deformable mirror, Shack-Hartman wavefront sensor and 12 bit scientific-grade CCD array is presented. Light source for the AO retina camera is a superluminescent diode (SLD) coupled to a multimode fiber which reduces the spatial coherence of the SLD and eliminates the speckle noise in the image. The output from the multimode fiber provides a high-speed uniform-intensity source of illumination for the retina. Imaging rates of 4.8frames/s has...
屈军乐, JONNAL, R S THORN, K E MILLER, D T. 视网膜单细胞成像技术研究[J]. 激光生物学报, 2004, 13(3): 194. 屈军乐, JONNAL, R S THORN, K E MILLER, D T. Single Cell Imaging of the Living Human Retina[J]. Acta Laser Biology Sinica, 2004, 13(3): 194.
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