光子学报, 2004, 33 (1): 31, 网络出版: 2006-10-25
一种检测十二指肠胃返流光纤传感器的研制
Design of a Fiber-optic Sensor for Monitoring Duodenogastric Reflux
摘要
设计了可检测十二指肠胃返流的光纤传感器,该传感器由470
nm的信号光、595 nm参考光和光纤束构成,主要检测十二指肠返流物中的胆红素在470
nm与595 nm的吸光度,本文还对影响传感器检测的因素,诸如波长、pH、胃液中悬浮颗粒造成的散射作用以及其他的因素,做了详细评价.传感器可以达到10
mg/dl优良的动态响应范围,离体实验结果表明,该传感器可以作为临床动态检测手段.
nm的信号光、595 nm参考光和光纤束构成,主要检测十二指肠返流物中的胆红素在470
nm与595 nm的吸光度,本文还对影响传感器检测的因素,诸如波长、pH、胃液中悬浮颗粒造成的散射作用以及其他的因素,做了详细评价.传感器可以达到10
mg/dl优良的动态响应范围,离体实验结果表明,该传感器可以作为临床动态检测手段.
Abstract
A fiber-optic sensor for monitoring of duodenogastric reflux is fabricated. The sensing system, based on the principle of double-beam compensation, includes two diodes for light sources, blue at 470 nm as signal light and yellow at the wavelength of 595 nm as reference one, and a Y model fiber optic bundle for transmitting light. The sensor performs on detection of spectrophotometric absorption of bilirubin always present in entero-gastric reflux at 470 nm and 595 nm. A general evaluation of the sensor about factors affecting its detection is discussed in detail: Wavelength choice, pH, scattering effect resulting from gastric precipitates and others. The sensor shows a good excellent performance with a dynamic linear range of up to 10 mg/dl. The in-vitro experiment shows it can be used in clinical analysis of DGR
陈国平, 姜志茹, 夏荣民, 寿文德, 龚均. 一种检测十二指肠胃返流光纤传感器的研制[J]. 光子学报, 2004, 33(1): 31. 陈国平, 姜志茹, 夏荣民, 寿文德, 龚均. Design of a Fiber-optic Sensor for Monitoring Duodenogastric Reflux[J]. ACTA PHOTONICA SINICA, 2004, 33(1): 31.