Chinese Optics Letters, 2006, 4 (12): 722, Published Online: Dec. 30, 2006
Methods of calibration to optical trapping force upon non-spherical cells Download: 542次
生物医学光子学 光镊势阱 细胞光镊阱力 标定 玻尔兹曼统计法 均方位移法 170.0170 Medical optics and biotechnology 170.4580 Optical diagnostics for medicine
Abstract
The dynamical equation of a trapping cell is solved to find calibration methods for the trapping force, and two methods are compared by synthetic experiment data. Results indicate that: Boltzmann distribution method (BDM) is available for the force calibration of non-spherical or anisotropic cells in arbitrary trap potential; the mean square displacement method (MSDM) is available only for a symmetric harmonic optical trap. The spatial resolution requirement of the calibration system is about a nanometer. The results agree with the reported experiments.
Youli Yu, Zhenxi Zhang, Zheng Li, Xiaoli Wang. Methods of calibration to optical trapping force upon non-spherical cells[J]. Chinese Optics Letters, 2006, 4(12): 722.