建立了一套单模光纤型光学相干层析(OCT)成像系统,开展了动物眼睛的成像实验,实现了高信噪比、高分辨率、大成像深度的层析图像的获取。系统纵向分辨率达到9 μm,横向分辨率为10 μm,最大层析成像深度可达3.4 mm。实验图像和商业蔡氏三代光学相干层析技术成像的对比结果表明,研制的OCT系统已经能展示视网膜的基本分层结构,而且能分辨脉络膜的分层结构和脉络膜血管,后者是蔡氏三代OCT系统所无法实现的。

Single-mode fiber-designed optical coherence tomography (OCT) system is developed and applied in ophthalmic imaging. Images with high signal-to-noise ratio, high resolution and large image depth, are achieved by the developed system. The calibrated axial resolution and transversal resolution are 9 μm and 10 μm, respectively, and the maximum depth range is 3.4 mm. Comparison between experimental results and Zeiss OCT Ⅲ are presented. The results show that the proposes OCT system can image not only the layers of retina , but also the layers and vas of choroid which cannot be obtained by Zeiss OCT Ⅲ.