Chinese Optics Letters, 2008, 6 (12): 889, Published Online: Dec. 17, 2008
Experimental validation for time-domain fluorescence diffuse optical tomography of linear scheme Download: 646次
荧光扩散光层析 特征数据 时域 图像重建 时间相关单光子计数 170.3880 Medical and biological imaging 170.3660 Light propagation in tissues 170.6280 Spectroscopy, fluorescence and luminescence 170.6960 Tomography 170.3010 Image reconstruction techniques 170.6920 Time-resolved imaging
Abstract
We present a full three-dimensional, featured-data algorithm for time-domain fluorescence diffuse optical tomography that inverts the Laplace-transformed time-domain coupled diffusion equations and employs a pair of appropriate transform-factors to effectively separate the fluorescent yield and lifetime parameters. By use of a time-correlation single-photon counting system and the normalized Born formulation, we experimentally validate that the proposed scheme can achieve simultaneous reconstruction of the fluorescent yield and lifetime distributions with a reasonable accuracy.
Feng Gao, Limin Zhang, Jiao Li, Huijuan Zhao. Experimental validation for time-domain fluorescence diffuse optical tomography of linear scheme[J]. Chinese Optics Letters, 2008, 6(12): 889.