中国激光, 2009, 36 (1): 249, 网络出版: 2009-02-10
飞秒激光双光子制造生物微器件微支架
Manufacturing Micro-Biological Device and Scaffold Research with Two-Photon Femtosecond Laser Technology
激光技术 飞秒激光 微加工 双光子聚合 微生物器件 laser technique femtosecond laser micromachining two photon polymerization microbial device
摘要
介绍了飞秒激光双光子吸收和光聚合的机制, 将飞秒激光技术应用于生物相容性材料(ORMOCER)的三维微纳米加工中。在ORMOCER材料内实现了双光子光聚合, 最高加工精度达到0.5 μm, 突破了衍射极限。推导出双光子光聚合阈值的数学表达式, 研究了扫描速度V和激光功率P对横向尺寸的影响规律。在此基础上采用飞秒激光双光子微细加工技术制备了典型的微生物器件——微井阵列、微柱阵列和光子晶体生物微型支架。
Abstract
This paper reports the mechanism of two-photon absorption photopolymerization and the femtosecond laser technology used for biocompatible materials ORMOCER three-dimensional micro-nano processing.Two-photon absorption photopolymerization was achieved in ORMOCER resin, the resolution reached 0.5 μm less than the diffraction limitation. The mathematical expression of two photon photopolymerization threshold is derived, the effect of the scanning speed V and the laser power P on the transverse size is studied. Using two-photon femtosecond laser micro-processing technology fabricates a typical microbial devices such as micro-well array,micro-pole-array, and photonic crystal micro-biological scaffold.
狄建科, 周明, 杨海峰, 孔俊杰, 戴娟. 飞秒激光双光子制造生物微器件微支架[J]. 中国激光, 2009, 36(1): 249. Di Jianke, Zhou Ming, Yang Haifeng, Kong Junjie, Dai Juan. Manufacturing Micro-Biological Device and Scaffold Research with Two-Photon Femtosecond Laser Technology[J]. Chinese Journal of Lasers, 2009, 36(1): 249.
PDF全文
