光学学报, 2009, 29 (s1): 37, 网络出版: 2009-06-25
基于光纤扫描探头的扫频光学相干层析实时成像系统
Swept Source Optical Coherence Tomography based on Scanning Fiber Probe
医用光学与生物技术 光学相干层析成像 压电双晶片 扫频光源 medical optics and biotechnology optical coherence tomography piezoelectric bimorph swept source
摘要
扫频光学相干层析技术(SSOCT)相比于传统的时域OCT技术(TDOCT)在系统的成像速度和灵敏度方面都有了显著的提高, 已成为目前OCT领域的研究热点。报道了基于一维扫描光纤探头的SSOCT成像系统。该探头利用光纤悬臂的共振特性, 通过对压电陶瓷施加接近于该共振频率的驱动信号, 实现光纤悬臂的单驱动一维扫描。为了保证系统轴向分辨率, 需要对干涉光谱信号进行k空间标定, 系统采用基于马赫曾德尔干涉仪(MZI)的同步标定方法, 轴向分辨率达到8.3 μm。应用所研制的光纤扫描探头于SSOCT系统, 在20 kHz的A-Scan速率下, 成像速度达20 frame/s, 横向范围1 mm, 横向分辨率10 μm, 获得初步的实验结果, 验证了方案的可行性。
Abstract
Swept source optical coherence tomography (SSOCT) technique has recently become the hot topic of investigation because of its speed and sensitivity advantage over traditional time domain optical coherence tomography (TDOCT). Based on one dimensional scanning fiber cantilever probe, a SSOCT system is developed. The probe exploits resonance of a fiber cantilever which is excited by one piece of piezoelectric bimorph through a driving signal whose frequency is near the resonant frequency of the fiber cantilever. To achieve a high system axial resolution, the interference spectrum calibration in wave number domain is necessary. We report a calibration method based on Mach-Zender interferometer (MZI), and the system axial resolution achieves 8.3 μm. Based on the fiber cantilever probe, at 20 kHz A-Scan rate, the SSOCT system can get OCT images of sample at a frame rate of 20 frame/s, the lateral range of 1 mm, and the lateral resolution of 10 μm. Some preliminary imaging results presented in the paper demonstrate the feasibility of the scheme.
吴彤, 丁志华, 王凯, 徐磊, 陈明惠, 王川. 基于光纤扫描探头的扫频光学相干层析实时成像系统[J]. 光学学报, 2009, 29(s1): 37. Wu Tong, Ding Zhihua, Wang Kai, Xu Lei, Chen Minghui, Wang Chuan. Swept Source Optical Coherence Tomography based on Scanning Fiber Probe[J]. Acta Optica Sinica, 2009, 29(s1): 37.