中国激光, 2009, 36 (10): 2528, 网络出版: 2009-10-23
三维谱域光学相干层析成像系统的研制
Development of a Spectrum Domain 3D Optical Coherence Tomography System
医用光学和生物技术 光学相干层析 三维成像 视网膜成像 medical optics and biotechnology optical coherence tomography 3D imaging retina imaging
摘要
介绍了基于光纤迈克尔孙干涉仪的三维谱域光学相干层析(OCT)系统。系统探测器部分为自行研制的高速高分辨率光谱仪,其光谱分辨率高达0.05 nm,使OCT成像探测深度范围达3.4 mm。系统信噪比(SNR)测量值为51 dB,纵向分辨率8.5 μm。系统成像速率达10×103 line /s,通过二维扫描和三维重建,可达到2 s采集一幅三维OCT图像的速度。借助三维相干层析成像技术,可以对眼底视网膜等生物组织进行更加直观和精确的显示。
Abstract
We developed a 3D spectrum domain optical coherence tomography (OCT) system based on fiber-based Michelson interferometer. The measurable depth of the OCT imaging is up to 3.4 mm for the detection part is of high speed spectrometer with 0.05 mm spectrum resolution. The signal-noise-ratio (SNR) and axial resolution of this OCT system are experimentally found to be 51 dB and 8.5 m,respectively. A 3D OCT image could be acquired in two second owing to the fast A-scan rate (up to 10×103 line/s). Using 3D OCT technology,the images of biology tissue such as retina are shown more intuitive and precise.
段炼, 何永红, 朱锐, 马辉, 郭继华. 三维谱域光学相干层析成像系统的研制[J]. 中国激光, 2009, 36(10): 2528. Duan Lian, He Yonghong, Zhu Rui, Ma Hui, Guo Jihua. Development of a Spectrum Domain 3D Optical Coherence Tomography System[J]. Chinese Journal of Lasers, 2009, 36(10): 2528.
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