Chinese Optics Letters, 2010, 8 (2): 167, Published Online: Mar. 5, 2010  

High-resolution subsurface articular cartilage imaging based on Fourier-domain common-path optical coherence tomography Download: 590次

Author Affiliations
1 Department of Electrical and Computer Engineering, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA
2 Division of Electronics and Information Engineering, Center for Advanced Image and Information Technology, Chonbuk National University, Deokjin-Dong, Jeonju, 561-756, Korea
Abstract
We demonstrate the subsurface imaging of an articular cartilage using Fourier-domain common-path optical coherence tomography. The bare fiber probe integrated with a hypodermic needle provides the rigidness required to perform lateral scanning with less microscale bending. By submerging both the probe and the specimen into saline solution, we not only reduce the beam divergence, but also increase the signal-to-noise ratio compared with the measurement in free space. Our system can di?erentiate the characteristic cartilage zones and identity various micro-structured defects in an ex vivo chicken knee cartilage, thus demonstrating that it could be used to conduct early arthritis diagnosis and intraoperative endo-microscopy.

Jae-Ho Han, Xuan Liu, Jin U. Kang, Chul Gyu Song. High-resolution subsurface articular cartilage imaging based on Fourier-domain common-path optical coherence tomography[J]. Chinese Optics Letters, 2010, 8(2): 167.

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