Chinese Optics Letters, 2010, 8 (2): 167, Published Online: Mar. 5, 2010
High-resolution subsurface articular cartilage imaging based on Fourier-domain common-path optical coherence tomography Download: 590次
COT 成像系统 相干光学效应 光纤光学 110.4500 Optical coherence tomography 170.0110 Imaging systems 030.1670 Coherent optical effects 060.2310 Fiber optics
Abstract
We demonstrate the subsurface imaging of an articular cartilage using Fourier-domain common-path optical coherence tomography. The bare fiber probe integrated with a hypodermic needle provides the rigidness required to perform lateral scanning with less microscale bending. By submerging both the probe and the specimen into saline solution, we not only reduce the beam divergence, but also increase the signal-to-noise ratio compared with the measurement in free space. Our system can di?erentiate the characteristic cartilage zones and identity various micro-structured defects in an ex vivo chicken knee cartilage, thus demonstrating that it could be used to conduct early arthritis diagnosis and intraoperative endo-microscopy.
Jae-Ho Han, Xuan Liu, Jin U. Kang, Chul Gyu Song. High-resolution subsurface articular cartilage imaging based on Fourier-domain common-path optical coherence tomography[J]. Chinese Optics Letters, 2010, 8(2): 167.