针对冠状动脉的运动分析问题,本文提出基于弹性配准的血管骨架三维运动估计方法。在对X射线冠脉造影图像序列进行三维血管骨架序列重建的基础上,寻找两个时刻同一血管分支上点之间的对应关系,得到各点的运动向量。通过使适当的目标函数最小化,运用动态规划算法,得到最优匹配。通过采用运动场已知的模拟数据对算法精度进行定量估计,并采用临床图像序列进行实验,结果表明,算法具有较高的精度和较快的运算速度。

An approach for estimating three-dimensional motion field of cardiac vessel axes recovered from X-ray angiographic sequences based on elastic registration is proposed.Displacement vector of each skeleton point is obtained by matching vascular axes at consecutive instants in point-by-point manner.A proper cost function is minimized to acquire the global optimal match by using the algorithm of dynamic programming.The accuracy of the method was quantitatively assessed by using computer-simulated data with known transformation parameters.Experiments with clinical data were also carried out.Results show the validity of the method.