光谱学与光谱分析, 2010, 30 (8): 2124, 网络出版: 2011-01-26  

六味地黄丸指纹图谱的近红外光谱分析方法的建立

Analysis Method of the Fingerprint of LiuWei DiHuang Pills by Near Infrared Spectroscopy
作者单位
1 中国航天员科研训练中心, 北京100094
2 北京同仁堂科技发展股份有限公司, 北京100079
3 中国农业大学信电学院, 北京100083
摘要
建立了一种近红外光谱测定六味地黄丸指纹图谱的方法。 应用毛细管电泳法建立六味地黄丸指纹图谱, 计算其相似度, 同时测定其近红外光谱, 建立六味地黄丸指纹图谱相似度与近红外光谱之间的数学模型。 通过对模型的优化, 建模集样品的相关系数(r)、 校正标准差和平均相对误差分别为0.904 6, 0.058和6.12%, 表明六味地黄丸指纹图谱相似度实测值与预测值之间有较好的线性关系。 研究结果表明以基于指纹图谱的近红外光谱法用于六味地黄丸的质量控制具有可行性。
Abstract
The purpose of the present paper is to establish a method of the fingerprint of LiuWei DiHuang pills by the near infrared spectroscopy. First, the authors established the fingerprint of LiuWei DiHuang pills by high performance capillary electrophoresis (HPCE), and calculated its similarity. At the same time, the authors scanned its near infrared spectrogram. Then the authors established the mathematical model between the similarity of fingerprint and the near infrared spectrogram. Through the optimization of the model, the correlation(r), calibration standard deviation and the average relative error of the modeling set were 0.904 6, 0.058 and 6.12%, respectively. It proved that the linearity between calculated and forecast of fingerprint was clear. The results showed that the method of the fingerprint of LiuWei DiHuang pills by the near infrared spectroscopy was feasible.

陈斌, 李军会, 臧鹏, 于燕波, 田瑞华, 严勇朝, 迟玉明, 张录达, 严衍禄. 六味地黄丸指纹图谱的近红外光谱分析方法的建立[J]. 光谱学与光谱分析, 2010, 30(8): 2124. CHEN Bin, LI Jun-hui, ZANG Peng, YU Yan-bo, TIAN Rui-hua, YAN Yong-chao, CHI Yu-ming, ZHANG Lu-da, YAN Yan-lu. Analysis Method of the Fingerprint of LiuWei DiHuang Pills by Near Infrared Spectroscopy[J]. Spectroscopy and Spectral Analysis, 2010, 30(8): 2124.

关于本站 Cookie 的使用提示

中国光学期刊网使用基于 cookie 的技术来更好地为您提供各项服务,点击此处了解我们的隐私策略。 如您需继续使用本网站,请您授权我们使用本地 cookie 来保存部分信息。
全站搜索
您最值得信赖的光电行业旗舰网络服务平台!