苯酚、间甲酚和百里酚由于光谱重叠严重，用常规的分析法较难直接检测。采用三维荧光光谱技术与平行因子分析相结合的方法可同时测定苯酚、间甲酚和百里酚。结果表明，在苯酚、间甲酚和百里酚共同存在下，用平行因子算法得到的苯酚和百里酚分辨结果较好，平均回收率分别为(95.23±2.55)%和(102.8±1.97)%；间甲酚得到的分辨质量浓度偏离实际质量浓度较大。同时，研究了3种酚类的两两混合物，得到的结果优于3种酚类共同存在下得到的结果，用品质因子评估了算法的准确性。实验结果表明，用平行因子算法与三维荧光光谱分析相结合能够同时测定苯酚、间甲酚和百里酚混合物，选择性好，检出限可达1 μg/L。

It is difficult to determine the mixtures of phenol, m-cresol and thymol directly by routine analytical method since their fluorescent spectra are overlapped closely. Excitation-emission matrix fluorescence technology combined with parallel factor (PARAFAC) algorithm is used to determine phenol, m-cresol and thymol simultaneously. Results show that the concentrations of phenol and thymol resolved by PARAFAC are better than the actual one when three compounds are determined simutaneously, and the average recoveries are (95.23±2.55)% and (102.8±1.97)% respectively. However, the result of m-cresol is not satisfied, and the resolved concentration deviates from the actual one severely. Moreover, two component compounds mixed with each other among phenol, m-cresol and thymol are also studied, and the result is better than that obtained in the mixtures contained all of three phenolic compounds. In addition, the accuracy of the PARAFAC algorithm is also evaluated through figures of merit. The method using excitation-emission fluorescence combined with PARAFAC algorithm can determine phenol, m-cresol and thymol simultaneously with a good selectivity, and the limit of detection achieves to 1 μg/L.