漫反射光谱人体成分检测研究中，光纤探头接收漫反射光子穿透深度及传输路径对检测效率及灵敏度影响较大，而传统的检测光纤探头无法实现对特定深度漫反射光子选择性接收。针对人体成分检测需要，提出了采用一定入射接收角度及半球透镜耦合的漫反射测量光纤探头结构。在三层皮肤模型基础上，结合光纤探头形式改进Monte Carlo程序，计算光纤探头接收漫反射光子穿透深度，有效光子比例，有效信息载荷以及真皮层检测灵敏度。结果表明，设计的光纤探头可实现真皮层漫反射光子选择性接收，检测效率以及测量光谱受非目标层组织结构及光学参数影响较小，可有效提高人体成分无创检测灵敏度。

Diffuse reflectance spectroscopy is widely applied in non-invasive detection of human tissue. Depth and transmission path of detecting photons may influence the sensitivity and accuracy of spectral detection. The conventional fiber-optic probes with parallel illumination-collection fibers vertical to skin tissue cannot selectively collect scattered photons from specific penetration depth. For the purpose of human components sensing, the present work designs the specific fiber probes configuration with certain illumination-collection angle or half-ball lens coupled to improve the detection efficiency of dermis. Based on three layers tissue model, Monte Carlo simulation is modified and applied to evaluate the penetration depth of detected photons, percentage of effective photons, effective information loading and detection sensitivity of dermis with each fiber probes. The results indicate that probes proposed in this paper improve the detection efficiency and sensitivity of dermis and the effect of the changes of tissue structure of non-target layer and optical parameters on it is small.