摘要

针对本课题组早些时候研制的用于微量组织液透皮抽取的微流控芯片, 研究了一种基于偶氮双异丁腈(azobisisobutyronitrile, AIBN)热分解产生气体的微型正压源, 用于为微流控芯片中微量组织液的收集和输运提供驱动力。将AIBN固定到微型加热器上, 微型加热器加热AIBN至70 ℃即可产生一定的正压力。实验结果表明, 设计的微型正压源压力可控、易于制造、体积小, 8.7 mg的AIBN在900 mA加热电流下可产生182 kPa的压力, 满足对微流控芯片中组织液透皮抽取所需的驱动力。

Abstract

In order to provide the driving force for the collection and transport of the micro liquid in a microfluidic chip developed by our research group in earlier research, this paper presents a micro positive pressure generator based on the released gas by thermal decomposition of azobisisobutyronitrile (AIBN). The AIBN is fixed to a micro-heater and heated to 70 ℃ to produce a certain amount of positive pressure. Experimental measurements show that this micro positive pressure generator can obtain 182 kPa pressure with heating 8.7 mg of AIBN by a heating current of 900 mA. The designed micro positive pressure generator is a smaller size, pressure controllable and easy to produce, and obtained pressure can satisfy the requirements of transdermal interstitial fluid (ISF) extraction.

补充资料

中图分类号：O35;TP273

DOI：10.3788/ope.20122010.2245

所属栏目：微纳技术与精密机械

基金项目：国家自然科学基金资助项目(No.61176107);天津市科技支撑计划重点项目(No.11ZCKFSY01500);国家公益性行业科研专项重点项目(No.GYHY2009060371)

收稿日期：2012-06-14

修改稿日期：2012-07-17

网络出版日期：--

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联系人作者：栗大超(dchli@tju.edu.cn)

备注：栗大超(1976-), 男, 河南人, 博士, 副教授, 硕士生导师, 2004年于天津大学精密仪器及机械专业获得工学博士学位, 2006~2008年于美国CWRU大学电子工程系从事博士后研究工作, 主要从事微系统技术与微型仪器、生物医学检测技术、精密测试技术及仪器等领域的研究。

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引用该论文

LI Da-chao,JI Yong-jie,YU Hai-xia,LIANG Wen-shuai,Xu Ke-xin. Micro positive pressure generator based on AIBN for driving micro fluid[J]. Optics and Precision Engineering, 2012, 20(10): 2245-2250

栗大超,姬永婕,于海霞,梁文帅,徐可欣. 基于AIBN材料的微流体驱动用微型正压源[J]. 光学 精密工程, 2012, 20(10): 2245-2250