中国激光, 2002, 29 (s1): 658, 网络出版: 2013-02-23  

几种波长激光对离体猪心经外膜打孔的组织学研究

Histonic Study on Creating Myocardial Channel with Several Lasers in Isolated Porcine Myocardium
作者单位
1 华中科技大学 同济医学院协和医院, 武汉 430074
2 华中科技大学 激光技术国家重点实验室, 武汉 430074
摘要
研究不同工作参数下几种波长的激光对离体猪心经外膜打孔的组织学变化,寻找适合心外膜打孔的激光源及最佳工作参数。用自制的波长为1320 nm和1060 nm的Nd:YAG激光,532 nm KTP倍频Nd:YAG 激光,以多种工作参数对离体猪心经外膜激光打孔,与进口的波长为2100 nm的Ho:YAG激光比较,记录形成一个透壁孔道所需的触发次数。在相应的工作参数下,ΚΤΡ倍频Nd:YAG激光与目前应用的Ho:YAG激光类似,能以较少的触发次数形成激光孔道,且所形成的孔道具有热损伤小的优点。
Abstract
The effects of several lasers such as Ho:YAG, Nd:YAG frequency-doubled Nd:YAG lasers, on creating transmural channel in isolated swine heart were investigated. Light microscopy was used to assess the histologic characteristics of laser-induced thermal damage and the channels diameter. The pulse number of creating a transmural channel was recorded. The results showed that the frequency-double Nd:YAG laser, as well as Ho: YAG can effectly creat the transmural channel with less thermal damage.

曾秋棠, 蒋桔泉, 曹林生, 邓中龙, 李正佳, 朱长虹. 几种波长激光对离体猪心经外膜打孔的组织学研究[J]. 中国激光, 2002, 29(s1): 658. ZENG Qiu-tang, JIANG Ju-quan, CAO Lin-sheng, DENG Zhong-long, LI Zheng-jia, ZHU Chang-hong. Histonic Study on Creating Myocardial Channel with Several Lasers in Isolated Porcine Myocardium[J]. Chinese Journal of Lasers, 2002, 29(s1): 658.

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