激光与光电子学进展, 2013, 50 (8): 080005, 网络出版: 2013-08-08
多普勒光学相干层析成像研究进展 
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Advances in Doppler Optical Coherence Tomography
医用光学 光学相干层析成像 多普勒成像 互相关 矢量速度 正交色散 medical optics optical coherence tomography Doppler imaging cross correlation vector velocity orthogonal dispersion
摘要
光学相干层析成像技术(OCT)自诞生至今已得到了飞速发展和广泛应用。多普勒OCT是OCT在功能成像方面的重要拓展。介绍了谱域OCT(SD-OCT)系统及其在小鼠脑部血管血流的动态监测和微流控芯片流场测量中的典型应用，报道了本课题组在多普勒成像方法与系统研制方面的最新进展，包括用于多普勒成像的高级互相关相位获取新方法，用于矢量速度测量的二区分束与渡越时间分析方法，以及超大量程正交色散SD-OCT系统及其相位成像应用。
Abstract
Rapid developments and wide applications of optical coherence tomography (OCT) have been achieved since its first coming into being. Doppler OCT is an important functional extension of existing OCT imaging modality. Spectral domain OCT (SD-OCT) system and its applications in dynamic monitoring of blood flow in a rat brain model and three-dimensional flow-field measurement of a microfluidic chip are presented. Recent advances in Doppler imaging method and system developments are reported, including sensitive phase retrieval for Doppler imaging through higher-order cross-correlation, vector-velocity quantification by two-zone beam divider and transit-time analysis, ultralong-range orthogonal dispersive SD-OCT system and its application in phase-sensitive imaging.
丁志华, 赵晨, 鲍文, 沈毅, 王川, 黄良敏, 吴兰, 杜持新. 多普勒光学相干层析成像研究进展[J]. 激光与光电子学进展, 2013, 50(8): 080005. Ding Zhihua, Zhao Chen, Bao Wen, Shen Yi, Wang Chuan, Huang Liangmin, Wu Lan, Du Chixin. Advances in Doppler Optical Coherence Tomography[J]. Laser & Optoelectronics Progress, 2013, 50(8): 080005.
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