在含有Sr2+, Ca2+, PO3-4和壳聚糖(CHI)的电沉积液中, 用恒电流沉积法, 在医用纯钛(Ti)表面上得到壳聚糖/掺锶羟基磷灰石(SrHAP)复合涂层。 采用扫描电镜(SEM)、 能量弥散X射线谱(EDS)、 X射线衍射(XRD)对涂层进行检测, 用傅里叶变换红外光谱(FTIR)考察了壳聚糖和锶离子的掺杂对HAP涂层构象和生物活性的影响。 结果表明: 锶部分取代磷灰石中的钙, 表面形貌由疏松的针状变为较致密的片状。 FTIR分析表明, 涂层中出现了典型的amideⅠ和amideⅡ的壳聚糖振动峰, 则CHI与SrHAP杂化良好; 模拟生理液浸泡后表面覆盖有球状类骨磷灰石, 则涂层具备较好的生物活性。 塔菲尔测试表明, 复合涂层使得Ti表面的抗生理腐蚀性显著提高。

Chitosan/strontium-substituted hydroxyapatite (CHI/SrHAP) coatings were prepared on titanium substrate by electrochemical deposition technique containing Sr2+, Ca2+, PO3-4 and Chitosan. The as-prepared coatings were examined by scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy (EDS), Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) tests. The results indicate that the CHI/SrHAP coatings take the morphology of flake-like rather than the needle-like crystal , and the composite coating becomes more compact. The FTIR test indicates that the typical vibration absorption peaks of chitosan (amideⅠand amideⅡ) emerged, simulated body fluid immersion test proved that the CHI/SrHAP coatings had induced carbonate-apatite formation, indicating that the composite coating possesses excellent biocompatibility. In the electrochemical corrosion testing, that the CHI/SrHAP coatings showed stronger corrosion resistance than pure Ti.