为了满足液晶母体在不同情况下的参数需求，合成了3种含有噁二唑结构的新型负性未知化合物用于液晶母体的调配。以芳烃的碘代物为原料，通过三步反应合成了该类新型化合物。通过核磁共振(NMR)、元素分析(EA)和红外光谱(FT-IR)等分析方法确认了分子结构；利用偏光显微镜(POM)、示差扫描量热仪(DSC)等测试手段，对该类化合物的液晶参数进行了测定。实验表明，该类新型的1,2,4-噁二唑类化合物具有较小的光学各向异性值（Δn = 0.107~0.118）和负值较大的介电各向异性值（Δε = -1.6 ~ -4.3），并且个别单体具有较宽的相列相温度范围。该类新型的1,2,4-噁二唑类化合物可以用于液晶母体的调配并改善部分性能，且制备方法原料易得，合成路线简单，收率较高，易于实现工业化生产。

In order to meet the different demands of the LCD matrix, a serious of 1,2,4-oxadiazoles compounds was synthesized.These compounds were synthesized from aryl iodides through three steps. Their constructions were confirmed by NMR, FT-IR and elemental analysis.The parameters and the performances of these compounds were measured by POM and DSC.Some of these 1,2,4-oxadiazoles compounds not only have small optical anisotropy(Δn = 0.107~0.118) and large negative dielectric anisotropy(Δε = -1.6 ~ -4.3), but also have a wide nematic phase temperature range.These compounds can be used in the LCD matrix to improve partial performance of the LCD. The preparation method is of simple operation and low cost, which can also realize industrialization easily.