量子电子学报, 2014, 31 (3): 368, 网络出版: 2014-06-03
高温烧结羟基磷灰石靶的细胞相容性
Cellular compatibility of hydroxyapatite target sintered at high temperature
材料 羟基磷灰石靶 高温烧结 钙磷比 细胞相容性 materials hydroxyapatite target sintering at high temperature ratio of Ca to P cellular compatibility
摘要
为研究高温烧结羟基磷灰石靶的细胞相容性,把纯度为99%的羟基磷灰石粉末压制成圆盘形靶, 在氩气中于800C高温下烧结成型。用X射线衍射仪和X射线光电子能谱仪对羟基磷灰石靶的结构组成进行检测。 用四氮唑盐比色法对羟基磷灰石靶的细胞相容性进行检测,检测结果表明:纯度为99%的羟基磷灰石粉末 在压制成型和800C高温烧结的过程中化学组成没有发生变化,羟基磷灰石靶中的平均粒径为78.2 nm, 结晶度为89.4%,Ca/P比值为1.592;具有很好的细胞相容性。
Abstract
In order to investigate cellular compatibility of hydroxyapatite(HA) target sintered at high temperature, the powder of 99% pure hydroxyapatite was pressed to discal targets and the targets were sintered at 800C in argon ambience. The microstructure and composition of targets were detected with X-ray diffractometer(XRD) and X-ray photoelectron spectroscopy(XPS). The cellular compatibility of targets was detected with methyl thiazolyl tetrazolium(MTT). The experimental result demonstrates the chemical composition of targets was not changed while the powder of hydroxyapatite was pressed to targets and the targets were sintered at 800C in argon ambience. The average particle diameter in target was 78.2 nm, the crystallinity in target was 89.4% and the ratio of Ca to P in target was 1.592. The hydroxyapatite target sintered at 800C had cellular compatibility.
罗乐, 赵读亮, 蒋大鹏, 严中亚, 程光存, 方晓东. 高温烧结羟基磷灰石靶的细胞相容性[J]. 量子电子学报, 2014, 31(3): 368. LUO Le, ZHAO Du-liang, JIANG Da-peng, YAN Zhong-ya, CHENG Guang-cun, FANG Xiao-dong. Cellular compatibility of hydroxyapatite target sintered at high temperature[J]. Chinese Journal of Quantum Electronics, 2014, 31(3): 368.