为提高胆红素的光降解效应和新生儿黄疸病光疗的效果，设计研制了一种新生儿黄疸治疗仪用发光二极管(LED)光源。以实验测试的体外游离的标准胆红素溶液最有效的吸收光谱作为黄疸治疗仪光源的目标光谱，采用市面上现有的峰值波长和半峰全宽的不同单色LED 作为匹配光源，将简单遗传算法作为光谱匹配算法，进行了光源光谱的匹配设计、样灯制作和光谱测试与分析。结果表明：拟合的光谱与目标光谱匹配度达到了97.62%，实际的黄疸治疗仪光源样品的光谱与目标光谱的匹配度达到了93.08%，窄带宽的单色LED 能够匹配出所需要的目标光谱，光谱匹配度高，为新生儿黄疸光疗仪用光源的选择提供了研究的基础。

In order to improve bilirubin degradation effect and neonatal jaundice phototherapy efficiency, a light source of light-emitting diode (LED)-based neonatal jaundice therapeutic device (NJTD) is designed and developed. The most efficient absorption spectrum of standard bilirubin in vitro tested by the experiment is regarded as the target spectrum of NJTD light source. The commercial available monochromatic LEDs with different peak wavelengths and full width at half maximum (FWHM) are used as matching sources, and the simple genetic algorithm (SGA) is introduced as the spectral matching method. The spectral matching design is realized for the light source of the novel NJTD, and subsequently, the light sample model is developed, the corresponding spectrum is measured and the effect is analyzed finally. Results show that the fitted spectrum is in close proximity to the target spectrum with 97.62% matching degree, the spectrum of the light sample model developed is very comparable to the target spectrum with 93.08% matching degree，monochrome LEDs with narrow bandwidth can match the required target spectrum perfectly. The spectral matching degree is higher, which provides research foundation for the selection of LED-based NJTD light source.