在不同功率激光照射下, 纳米金与周围介质会经历不同的物理学效应, 并产生宏观、微观和纳观三个层次的生物学效应及相应的应用。其中纳观效应的生物学应用和机理研究受到了关注并具有挑战性。本文针对纳米金激光纳观热效应的物理学机理研究及其相应模型进行综述, 比较了各种模型和测量方法的利弊, 对其生物学应用进行了论述, 指出了其中的某些发展趋势, 强调了纳米金激光纳观热效应研究的必要性和重要性。

Upon laser heating, the GNP and the surrounding medium experience a number of different thermophysical responses depending on the laser power and GNP, leading to many biological responses and applications at the nano, micro and macroscale, in which the nanoscale responses and applications are most attractive and become one of the major challenge. This review covers the mechanism and its models of the nanoscale effect of laser activated gold nanoparticels, measurement of nanoscale heating and their advantages and disadvantages. The increasing and unprecedented biomedical applications are also mentioned here to emphasize the importance and necessity of the research in nanoscale heating of laser irradiated gold nanoparticles.