基于太赫兹金属光栅谐振传输现象, 利用金属光栅表面等离子体共振对周围介质敏感的特性, 设计了一种由金属光栅、样品池和高阻硅基底组成的免标记生物传感器.利用这种传感器在太赫兹时域光谱下测量了苏氨酸和精氨酸溶液的太赫兹透射光谱.结果表明：苏氨酸和精氨酸的共振频率随着溶液浓度改变在0.6～0.75 THz之间出现频移, 并且苏氨酸和精氨酸的混合样品的光谱并不是两者光谱的线性叠加.

Based on the Terahertz metal grating resonant transmission phenomenon, a label free biosensor consisting of metallic grating, sample pool and high resistivity silicon substrate was designed by using the sensitive characteristic of surface plasmon resonance of metallic grating for the surrounding medium. Terahertz transmission spectrums of threonine and arginine solutions were measured by using this sensor with terahertz time-domain spectroscopy. The experimental results show that, the resonance frequencies of the threonine and arginine solutions change and shift between 0.6 THz and 0.75 THz with the increase of concentration, moreover, the spectra of the mixed samples of threonine and arginine is not linear superposition of the two spectra.