光学学报, 2018, 38 (1): 0111001, 网络出版: 2018-08-31
基于动态散斑的光学相干层析成像技术 下载: 955次
Optical Coherence Tomography Based on Dynamic Speckle
成像系统 光学相干层析成像 动态散斑 三维血管构建 散斑频谱 imaging systems optical coherence tomography dynamic speckle three-dimensional vascular construction speckle frequency spectrum
摘要
在光学相干层析成像(OCT)技术中引入激光散斑的处理方法。首先在同一位置多次采集得到光谱信号,再对每个时刻所得光谱信号沿波矢方向进行傅里叶变换,解析得到同一位置每个时刻的OCT结构信息。然后对OCT结构信号沿时序方向进行傅里叶变换,得到散斑的频谱分布,最后在频谱区域中将动态散斑与静态散斑的比值定义为成像参数,以该比值构建的图像可以将样品图像中的流动区域凸显出来。仿体实验充分验证了该方法的可行性,将该方法用于鼠耳的血管区域提取并得到了鼠耳的三维血管图。
Abstract
Processing method of laser speckle imaging is introduced into optical coherence tomography (OCT). Spectra varying with time are acquired at the same position. The spectra at each moment are transformed into OCT structure by the Fourier transform along the direction of wave vector. The OCT structure information at the same position and different moments is solved, and is then computed along the dimension of time by the Fourier transform to obtain the frequency spectrum of speckle. Imaging parameter is defined as the ratio of dynamic speckle to static counterpart in the frequency spectrum. The phantom experiment demonstrates feasibility of the method. The method is also applied to extracting blood vessel of a mouse ear, and the three-dimensional vascular structure is obtained.
陈俊波, 曾亚光, 袁治灵, 唐志列. 基于动态散斑的光学相干层析成像技术[J]. 光学学报, 2018, 38(1): 0111001. Junbo Chen, Yaguang Zeng, Zhiling Yuan, Zhilie Tang. Optical Coherence Tomography Based on Dynamic Speckle[J]. Acta Optica Sinica, 2018, 38(1): 0111001.