稀土上转换荧光材料因为其独特的4f电子能级排布所带来的特殊光学、磁性等物理性质而受到研究人员的广泛关注。特别是其独特的反斯托克斯光学性质所带来的近红外激光响应及紫外至近红外光区内丰富的荧光发射性质, 更是被认为在荧光标记、生物成像、光学分析等领域具有重大的应用潜质。近些年, 伴随材料软化学制备方法的进步, 稀土上转换纳米材料的发光性质及其在多个领域内的应用研究取得了很大的进展。本文主要对稀土上转换荧光材料的发光性质调变及其在生物成像以及癌症治疗领域的应用研究进展加以阐述。

Due to its unique 4f electron configuration, the lanthanide upconversion fluorescence materials with special luminescence, magnetism properties have drawn considerable research attention in the world. Thereinto, the anti-Stokes upconversion luminescence property that can emit light in the field of UV to NIR region upon NIR laser also endow it with huge promising application potential in the field of fluorescence probe, bio-imaging, and fluorescence analysis. Recently, on account of big step of the development of the soft chemistry synthesis method, great progress of luminescence property and application of the lanthanide upconversion fluorescence materials have been made. Accordingly, in this work, we mainly focus on the recent research advances of the lanthanide upconversion luminescence modification and application in the field of bio-imaging and cancer therapy.