Journal of Innovative Optical Health Sciences, 2015, 8 (5): 1550018, Published Online: Jan. 10, 2019  

Carbon-coated magnetic particles increase tissue temperatures after laser irradiation

Author Affiliations
1 Key Laboratory of Specialty Fiber Optics and Optical Access Networks Shanghai University, 149 Yanchang Road Shanghai 200072, P. R. China
2 Institute of Biomedical Engineering, Shanghai University 149 Yanchang Road, Shanghai 200072, P. R. China
Abstract
Purpose: This work focused on the investigation the hyperthermia performance of the carboncoated magnetic particles (CCMPs) in laser-induced hyperthermia. Materials and methods: We prepared CCMPs using the organic carbonization method, and then characterized them with transmission electron microscopy (TEM), ultraviolet-visible (UV-Vis) spectrophotometry, vibrating sample magnetometer (VSM) and X-ray diffraction (XRD). In order to evaluate their performance in hyperthermia, the CCMPs were tested in laser-induced thermal therapy (LITT) experiments, in which we employed a fully distributed fiber Bragg grating (FBG) sensor to profile the tissue's dynamic temperature change under laser irradiation in real time. Results: The sizes of prepared CCMPs were about several micrometers, and the LITT results show that the tissue injected with the CCMPs absorbed more laser energy, and its temperature increased faster than the contrast tissue without CCMPs. Conclusions: The CCMPs may be of great help in hyperthermia applications.

Shupeng Liu, Na Chen, Fufei Pang, Zhengyi Chen, Tingyun Wang. Carbon-coated magnetic particles increase tissue temperatures after laser irradiation[J]. Journal of Innovative Optical Health Sciences, 2015, 8(5): 1550018.

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