Journal of Innovative Optical Health Sciences, 2014, 7 (1): 1350028, Published Online: Jan. 10, 2019  

CHARACTERISTIC FEATURES OF MUELLER MATRIX PATTERNS FOR POLARIZATION SCATTERING MODEL OF BIOLOGICAL TISSUES

Author Affiliations
1 Shenzhen Key Laboratory for Minimal Invasive Medical Technologies, Graduate School at Shenzhen Tsinghua University, Shenzhen 518055, P. R. China
2 Department of Physics, Tsinghua University, Beijing 100084, P. R. China
Abstract
We developed a model to describe polarized photon scattering in biological tissues. In this model, tissues are simplified to a mixture of scatterers and surrounding medium. There are two types of scatterers in the model: solid spheres and infinitely long solid cylinders. Variables related to the scatterers include: the densities and sizes of the spheres and cylinders, the orientation and angular distribution of cylinders. Variables related to the surrounding medium include: the refractive index, absorption coefficient and birefringence. In this paper, as a development we introduce an optical activity effect to the model. By comparing experiments and Monte Carlo simulations, we analyze the backscattering Mueller matrix patterns of several tissue-like media, and summarize the different effects coming from anisotropic scattering and optical properties. In addition, we propose a possible method to extract the optical activity values for tissues. Both the experimental and simulated results show that, by analyzing the Mueller matrix patterns, the microstructure and optical properties of the medium can be obtained. The characteristic features of Mueller matrix patterns are potentially powerful tools for studying the contrast mechanisms of polarization imaging for medical diagnosis.

E DU, HONGHUI HE, NAN ZENG, CELONG LIU, YIHONG GUO, RAN LIAO, MINGHAO SUN, YONGHONG HE, HUI MA. CHARACTERISTIC FEATURES OF MUELLER MATRIX PATTERNS FOR POLARIZATION SCATTERING MODEL OF BIOLOGICAL TISSUES[J]. Journal of Innovative Optical Health Sciences, 2014, 7(1): 1350028.

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