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光学相干层析成像眼底视网膜三维图像去抖动方法

Dither Removing of Three-Dimensional Optical Coherence Tomography Retinal Image

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摘要

眼底视网膜病变是大部分眼科疾病的来源。光学相干层析成像(OCT)具有无创性、成像安全快速等特点,在临床上被广泛用于眼科疾病的诊断。针对OCT视网膜三维图像因抖动产生的扭曲变形问题,提出一种基于曲线拟合的OCT视网膜三维重建图像去抖动方法,即通过预处理提取OCT视网膜图像的边界,再利用最小二乘法曲线拟合来计算各帧切片图像的偏移量。结果表明:所提方法对OCT视网膜三维重建图像扭曲变形具有明显的校正作用。

Abstract

Fundus retinopathy is the cause of most ophthalmic diseases. Optical coherence tomography (OCT) has been widely used in the diagnosis of ophthalmic diseases because of its non-invasive and rapid imaging features. In this paper, a dither removing method is proposed for three-dimensional OCT retinal image based on curve fitting. The OCT retina image boundary is extracted by preprocessing, and the offset of each frame slice image is calculated by least squares curve fitting. The results show that the proposed method has a significant correction effect on the distortion of the OCT retina three-dimensional reconstructed images.

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中图分类号:R774.1;TP391.4

DOI:10.3788/aos201939.0317001

所属栏目:医用光学与生物技术

基金项目:科技部重大科学仪器设备开发专项(2016YFF0102000)、中国科学院先导专项(XDB02060000)、国家自然科学基金(61675226, 61378090)、中国科学院青年创新促进会项目

收稿日期:2018-08-28

修改稿日期:2018-10-14

网络出版日期:2018-10-25

作者单位    点击查看

汪权:电子科技大学光电科学与工程学院, 四川 成都 610054
朋汉林:电子科技大学光电科学与工程学院, 四川 成都 610054
汪平河:电子科技大学光电科学与工程学院, 四川 成都 610054
樊金宇:中国科学院苏州生物医学工程技术研究所, 江苏 苏州 215163
刘敬璇:中国科学院苏州生物医学工程技术研究所, 江苏 苏州 215163
史国华:中国科学院苏州生物医学工程技术研究所, 江苏 苏州 215163

联系人作者:史国华(ghshi_lab@126.com)

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引用该论文

Wang Quan,Peng Hanlin,Wang Pinghe,Fan Jinyu,Liu Jingxuan,Shi Guohua. Dither Removing of Three-Dimensional Optical Coherence Tomography Retinal Image[J]. Acta Optica Sinica, 2019, 39(3): 0317001

汪权,朋汉林,汪平河,樊金宇,刘敬璇,史国华. 光学相干层析成像眼底视网膜三维图像去抖动方法[J]. 光学学报, 2019, 39(3): 0317001

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