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Multi-frame speckle reduction in OCT using supercontinuum pumped by noise-like pulses

Multi-frame speckle reduction in OCT using supercontinuum pumped by noise-like pulses

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Abstract

In most coherent imaging modality, speckle noise is a major cause that blurs the boundary of tissues and degrades the image contrast. By utilizing the unique properties of supercontinuum (SC) generated by noise-like pulses (NLPs) and a simple multi-frame averaging technique, we achieved significant speckle reduction in spectral domain optical coherence tomography (SD-OCT). We quantitatively compared the speckle of our proposed method with those of conventional swept source OCT (SS-OCT) and SD-OCT based on commercial light sources. The experimental results show that SC pumped by NLPs combined with noncoherent averaging method achieves better denoising performance in terms of contrast to noise ratio (CNR).

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DOI:10.1142/s1793545819500093

基金项目:This research was supported by the National Natural Science Foundation of China (61227807, 61575108 and 61505034), Tsinghua Initiative Scientific Research Program (2013THZ02-3). C. L. Pan and Y. J. You were supported in part by the Ministry of Science and Technology, Taiwan, under Grant 103-2622-E-007-006-CC2 and by the National Tsing Hua University Research Program Grant 104N2711E1. C.L. Pan is also supported by the Air Force O±ce of Scientific Research FA2386-13-1-4086.

收稿日期:2018-11-26

修改稿日期:2019-02-17

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Chengming Wang:State Key Laboratory of Low-Dimensional Quantum Physics, Department of Physics, Tsinghua University, Collaborative Innovation Center of Quantum Matter, Beijing, P. R. ChinaNuctech Company Limited, Beijing, P. R. China
Yi-Jing You:Department of Physics, National Tsing Hua University, No. 101, Sec. 2, Kuang-Fu Rd, Hsinchu, Taiwan
Shengnan Ai:State Key Laboratory of Low-Dimensional Quantum Physics, Department of Physics, Tsinghua University, Collaborative Innovation Center of Quantum Matter, Beijing, P. R. China
Wenxin Zhang:State Key Laboratory of Low-Dimensional Quantum Physics, Department of Physics, Tsinghua University, Collaborative Innovation Center of Quantum Matter, Beijing, P. R. China
Wenchao Liao:State Key Laboratory of Low-Dimensional Quantum Physics, Department of Physics, Tsinghua University, Collaborative Innovation Center of Quantum Matter, Beijing, P. R. China
Xiao Zhang:School of Life Science, Beijing Institute of Technology, Beijing, P. R. China
Juicheng Hsieh:State Key Laboratory of Low-Dimensional Quantum Physics, Department of Physics, Tsinghua University, Collaborative Innovation Center of Quantum Matter, Beijing, P. R. China
Ning Zhang:Institute of Forensic Science Ministry of Public Security, Beijing, P. R. China
Bihua Tang:Southwest Medical University, Luzhou, Sichuan Province, P. R. China
Ci-Ling Pan:Department of Physics, National Tsing Hua University, No. 101, Sec. 2, Kuang-Fu Rd, Hsinchu, TaiwanDepartment of Physics and Institute of Photonics Technologies, National Tsing Hua University, Taiwan
Ping Xue:State Key Laboratory of Low-Dimensional Quantum Physics, Department of Physics, Tsinghua University, Collaborative Innovation Center of Quantum Matter, Beijing, P. R. China

联系人作者:Ping Xue(xuep@tsinghua.edu.cn)

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引用该论文

Chengming Wang,Yi-Jing You,Shengnan Ai,Wenxin Zhang,Wenchao Liao,Xiao Zhang,Juicheng Hsieh,Ning Zhang,Bihua Tang,Ci-Ling Pan,Ping Xue. Multi-frame speckle reduction in OCT using supercontinuum pumped by noise-like pulses[J]. Journal of Innovative Optical Health Sciences, 2019, 12(2): 1950009

Chengming Wang,Yi-Jing You,Shengnan Ai,Wenxin Zhang,Wenchao Liao,Xiao Zhang,Juicheng Hsieh,Ning Zhang,Bihua Tang,Ci-Ling Pan,Ping Xue. Multi-frame speckle reduction in OCT using supercontinuum pumped by noise-like pulses[J]. Journal of Innovative Optical Health Sciences, 2019, 12(2): 1950009

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