以聚十二内酰胺(PA12)和羟基磷灰石(HA)为实验材料,采用选择性激光烧结(SLS)技术成形具有优良力学性能的PA12/HA复合材料多孔支架。首先,利用响应面法得到最佳的工艺参数组合,并运用该参数组合成形PA12/HA复合材料多孔支架;然后,在L9(3 4)正交实验的基础上,研究了孔型、孔隙率和HA比例三因素对多孔支架力学性能的影响。结果表明:SLS最优工艺参数组合为激光功率27.5 W、扫描间距0.12 mm、扫描速率1500 mm/s;不同因素对PA12/HA多孔支架压缩强度的影响程度由大到小依次为孔隙率、孔型和HA比例;当孔隙率为60%、孔型为圆形、HA比例为15%时,压缩强度最大,为8.04 MPa;当孔隙率为80%、孔型为方形、HA比例为15%时,压缩强度最小,仅为0.26 MPa。

Herein, porous scaffolds were fabricated from polylaurylamide (PA12)/hydroxyapatite (HA) composite using selective laser sintering (SLS). First, the response surface method was adopted to obtain the optimal process parameters, and the porous scaffolds of PA12/HA were manufactured employing these optimized parameters. The influences of pore type, porosity, and HA ratio on the mechanical properties of the porous scaffolds were then studied based on the L₉(3 ⁴) orthogonal test. Results show that the laser power of 27.5 W, scanning spacing of 0.12 mm, and scanning speed of 1500 mm·s ^-1 are the optimal combination of process parameters. Porosity has the biggest effect on the compressive strength of porous scaffolds, followed by pore type and HA ratio. The maximum compressive strength is 8.04 MPa when the porosity is 60%, the pore type is circular, and the HA ratio is 15%. The minimum strength of 0.26 MPa is obtained when the porosity is 80%, the pore type is square, and the HA ratio is 15%.