光学学报, 2019, 39 (10): 1030003, 网络出版: 2019-10-09
同型半胱氨酸的太赫兹特征吸收光谱分析 下载: 1126次
Terahertz Characteristic Absorption Spectrometric Analysis of Homocysteine
光谱学 同型半胱氨酸 密度泛函理论 太赫兹时域光谱 spectroscopy homocysteine density functional theory terahertz time-domain spectra
摘要
对同型半胱氨酸的太赫兹特征吸收光谱进行分析。首先使用密度泛函理论分析同型半胱氨酸分子的振动和转动模式,确保其理论吸收峰位于太赫兹光谱系统可测试范围内;然后,基于太赫兹时域光谱系统测量不同浓度同型半胱氨酸的特征吸收光谱,结合线性拟合方程精确反推出待测同型半胱氨酸的浓度。这些结果对于临床医学中同型半胱氨酸相关疾病的快速准确诊断具有重要意义。
Abstract
We investigate the terahertz characteristic absorption spectra of homocysteine. First, we use the density functional theory to analyze the vibration and rotation modes of homocysteine and ensure that the theoretical absorption peak is within the testing range of the terahertz spectroscopy system. Subsequently, the characteristic absorption spectra of homocysteine with different concentration are measured based on the terahertz time-domain spectroscopy system, which can be accurately performed using the linear fitting equation. These results exhibit considerable significance for the accurate and rapid diagnosis of homocysteine-related diseases in clinical medicine.
王莹莹, 汪丽平, 李恬, 严俊, 彭滟. 同型半胱氨酸的太赫兹特征吸收光谱分析[J]. 光学学报, 2019, 39(10): 1030003. Yingying Wang, Liping Wang, Tian Li, Jun Yan, Yan Peng. Terahertz Characteristic Absorption Spectrometric Analysis of Homocysteine[J]. Acta Optica Sinica, 2019, 39(10): 1030003.