Author Affiliations
Abstract
Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China
Multiphoton microscopy is the enabling tool for biomedical research, but the aberrations of biological tissues have limited its imaging performance. Adaptive optics (AO) has been developed to partially overcome aberration to restore imaging performance. For indirect AO, algorithm is the key to its successful implementation. Here, based on the fact that indirect AO has an analogy to the black-box optimization problem, we successfully apply the covariance matrix adaptation evolution strategy (CMA-ES) used in the latter, to indirect AO in multiphoton microscopy (MPM). Compared with the traditional genetic algorithm (GA), our algorithm has a greater improvement in convergence speed and convergence accuracy, which provides the possibility of realizing real-time dynamic aberration correction for deep in vivo biological tissues.
multiphoton microscopy 1700-nm window adaptive optics covariance matrix adaptation evolution strategy Chinese Optics Letters
2023, 21(5): 051701
山东大学信息科学与工程学院，山东 济南 250100
飞秒光参量放大技术是一种获得宽带飞秒脉冲的有效手段。首先介绍了飞秒光参量放大技术的基本原理，并通过数值模拟显示了群速度失配及位相失配对信号转换过程的影响。数值计算结果表明：群速度失配及位相失配会导致转换效率下降，群速度失配还会导致脉冲发生畸变。其次，综述了该技术在超短脉冲特别是周期量级脉冲产生方面的研究进展，并介绍了Baltuska等设计的可以产生3．9fs脉冲的非共线光参量放大装置。其中，详细讨论了超连续白光注入源、泵浦光角色散以及晶体选择三方面内容。最后介绍了该技术在高能飞秒脉冲产生方面取得的最新研究进展。
非线性光学 飞秒光参量放大 周期量级脉冲 超连续白光 泵浦光角色散 非共线光参量放大 高能飞秒脉冲 nonlinear optics femtosecond optical parametric amplification few-cycle pulse supercontinuum angular dispersion of pump beam noncollinear optical parametric amplification high-power femtosecond pulse
