本文建立了一套微波热声实时成像系统, 该系统由脉冲微波发生器, 多元环形探测器, 多通道数据采集装置和数据重建装置共同组成。在实验中, 利用填充盐水的两个塑料管验证其实时成像的性能, 结果表明, 该系统能够实现每秒16.7帧的成像速度。随后, 对活体小鼠的正常区域和肿瘤区域分别进行热声成像, 得到肿瘤和正常区域的对比度为1.7∶1, 证明了该系统在肿瘤检测中有较高的对比度。最后, 利用该系统监控细管趋近离体肿瘤的过程。因此该系统有望应用于实时监测。综上所述, 该热声成像系统具有无损, 成像速度快和大视场的良好性能, 有望在生物医学中得到广泛的应用, 尤其在肿瘤筛查和实时监控方面发挥作用。

A set of real-time microwave thermoacoustic imaging system was established. The system was composed of a pulsed microwave generator, a multi-element ring-shaped detector, a multi-channel data acquisition and a data reconstruction device. From experiments, the performance of the two plastic tubes filled with physiological saline was verified, and the results showed that the imaging speed was 16.7 frames per second. Subsequently, the normal and tumor area of the living mice were imaged, respectively, and the contrast between the tumor and normal area was 1.7∶1, which proved that the system had a high contrast in tumor detection. Finally, a dynamic process monitoring experiment was implemented. In summary, the established system has the advantage of non-invasive, fast imaging speed and large field of view, and is expected to be widely used in biomedicine, especially real-time tumor screening and monitoring.