In this paper, the recent progress on spectrally efficient single carrier (SC) 400G optical signal transmission was summarized. By using quadrature phase shift keying (QPSK), 16 quadrature amplitude modulation (16QAM) and 64QAM, we can realize transmission distance over 10000, 6000 and 3000 km, respectively, with large area fiber and all-Raman amplification. To improve the system performance and generate high-order QAM, advanced digital signal processing algorithms such as probabilistic shaping and look-up table pre-distortion are employed to improve the transmission performance.