利用静电纺丝技术制备了聚乙烯醇(PVA)/银纳米粒子高活性SERS柔性基底。将硝酸银、聚乙烯醇按照一定比例混合配置纺丝溶液，纺丝成膜后采用紫外光照射还原法得到纳米纤维基底。采用扫描电子显微镜(SEM)，透射电子显微镜(TEM),傅立叶红外光谱(FT-IR)，拉曼光谱(Raman)，紫外可见光谱(UV-Vis)等技术，对合成的纳米纤维基底进行表征。研究表明，银纳米颗粒呈球形分布在复合纤维中，粒径小于10 nm。以罗丹明为探针分子，硝酸银含量16wt%，紫外光照射3 h制备的基底具备最优的SERS性能。同时将此基底应用于烟酸药品检测，拉曼检测极限可达10-5 mol?L-1。

The flexible SERS substrate with high activity was prepared by electrospinning. The spinning solution was mixed with silver nitrate and polyvinyl alcohol in certain proportion. The nanofiber substrate was prepared by UV irradiation reduction method after spinning. The synthesized nanofiber substrate was characterized by Scanning electron microscopy (SEM), Transmission electron microscope (TEM), Fourier infrared spectroscopy (FT-IR), Raman spectroscopy, UV visible spectroscopy (UV-Vis). Research show that the silver nanoparticles are spherical in shape and less than 10 nm in diameter, distributed in composite fibers. Using rhodamine as probe molecule, the optimal SERS performance of the substrate is obtained, 16wt% of silver nitrate and 3 h of UV irradiation. At the same time, the substrate is applied to the detection of nicotinic acid drugs. The results show that the limit of Raman detection is 10-5 mol ? L-1.