利用近红外光谱法检测压疮易患组织血氧参数随压力的变化, 评估压力对血氧参数的影响。 方法: 实验人员30名, 其中老年人10人(平均年龄73.4 y), 脊椎损伤病人10人(平均年龄32 y), 健康青年人10名(平均年龄25 y)。 以此分三组, 健康青年人为对照组。 应用近红外光谱法测量血氧变化。 在静息状态下对实验者开始检测20 min, 然后施加20 kPa(150 mmHg)压力3 min。 压力释放后再检测20 min。 每位实验者实验时间共43 min。 老年人和脊椎损伤病人血氧参数随压力施加有明显变化(p<0.01), 且恢复到正常水平较健康人缓慢。 压力对压疮易患组织血氧参数有显著性影响, 表明血氧参数是评价压疮风险的良好指标。 应用近红外光谱法监测压疮易患组织血氧参数及评估压力影响是一种有效的方法。

The objective of the present study is to assess the effect of pressure on blood oxygenation in the sacrum tissue (high-risk area for pressure ulcer) based on near infrared spectroscopy (NIRS) signals. NIRS was used to detect the change in the value of blood oxygenation. Thirty subjects were recruited, of which ten were elders (average age, 73.4 y ), ten were persons with spinal cord injury (average age, 32 y) and ten were healthy persons (average age, 25 y). In resting conditions, the blood oxygenation in sacrum tissue of the 30 subjects was monitored for 20 minutes prior to and after the three-minute loading period. The results show that the first three oxygenation parameters in the elderly and persons with spinal cord injury (SCI) changed significantly during the loading period (p<0.01) and took longer time to return to the normal level than the health persons. TOI in the three groups decreased with the pressure and returned after pressure release. These findings indicated that pressure had significant effect on blood oxygenation and the oxygenation parameters are good indicators of evaluation of pressure sore risk.