数字化微喷射用直列微喷嘴制作工艺

张晓乐; 侯丽雅; 章维一

光学精密工程, 2008, 16 (11): 2222, 网络出版: 2010-02-28

数字化微喷射用直列微喷嘴制作工艺

Fabrication of in-line micropipette for digital micro-jetting experiment

论文大纲

张晓乐 ^*侯丽雅章维一

作者单位

南京理工大学机械工程学院,江苏南京 210094

微流体微喷嘴微流体数字化微阵列微喷射 microfluid micropipettes digitalization of microfluid technology microarray micro-jetting

摘要

为解决玻璃微管道拉制工艺制作的单孔微喷嘴存在容易脆断,微管道长度不易控制,微喷射效率低等问题,提出了一种新的微喷嘴制作工艺。该工艺延续了微喷嘴拉制工艺中非IC工艺和低成本的制作特点,仍以低流阻的圆截面为喷口形状,通过材料流变运动和冷却时收缩率不同,将多根微管道紧密嵌入到塑料管中;通过毛细腐蚀作用,制作出变内径的锥形管,并实现微喷管长度的控制。制作了内径50μm的4孔微喷嘴和10孔微喷嘴,锥管长为750μm,微喷管长2.5mm。使用制作的微喷嘴在微流体数字化驱动平台上进行了水性液体在油相和气相中的微喷射实验,制备了80μm的微滴和微滴阵列。实验表明,该工艺制作的直列微喷嘴可以在微流体数字化驱动下实现较好的数字化微喷射效果。

Abstract

A new non-IC method for fabricating micropipettes was presented to improve traditional micropipette fabrication from pulling of glass capillary to solve problems such as easily brittle fracture,hard to control length of microchannel and low efficiency of micro-jetting.By choosing the round cross section with lower flow resistance as the nozzle shape and embedding the multi-microchannels tightly into the plastic pipe by employing the rheologic flowing of plastic and the different shrinkage ratios of two materials in cooling,a conical pipe connecting microchannels and plastic pipe were formed by capillary and corrosion action.Meanwhile,the length of micronozzle was reduced.fabricated conical pipe characteristics by low cost,simple manipulation and safe process.The micropipettes with 4 and 10 micronozzles in inner diameter of 50 μm,and the length of 2.5 mm for micronozzle were fabricated,and the length of the conical pipes was 750 μm.The experiments of micro-jetting of aqueous liquid into oil phase and gaseous phase were carried out by employing digitalization of microfluid technology with the micropipettes and the microarray and micro-droplets with diameter of 80 μm were prepared.The experiments show that the micropipettes can well work at digitalization of microfluids technology.

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张晓乐, 侯丽雅, 章维一. 数字化微喷射用直列微喷嘴制作工艺[J]. 光学精密工程, 2008, 16(11): 2222. ZHANG Xiao-le, HOU Li-ya, ZHANG Wei-yi. Fabrication of in-line micropipette for digital micro-jetting experiment[J]. Optics and Precision Engineering, 2008, 16(11): 2222.

数字化微喷射用直列微喷嘴制作工艺

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