[1] . Copper[J]. Clin. Toxicol., 1999, 37(2): 217-230.

[2] . Trace elements in human physiology and pathology[J]. Biomed. Pharmacother, 2003, 57(9): 386-398.

[3] . Coumarin-derived Cu2+-selective fluorescence sensor: Synthesis, mechanisms, and applications in living cells[J]. J. Am. Chem. Soc., 2009, 131(5): 2008-2012.

[4] . Molecular mechanisms of copper uptake and distribution[J]. Curr. Opin. Chem. Biol., 2002, 6(2): 171-180.

[5] . Molecular mechanisms of the Menkes disease protein[J]. J. Biochem. Mol. Toxicol., 1999, 13(2): 93-106.

[6] . Copper in disorders with neurological symptoms: Alzheimers, Menkes, and Wilson diseases[J]. Brain Res. Bull., 2001, 55(2): 175-185.

[7] . The molecular basis of copper-transport diseases[J]. Trends Mol. Med., 2001, 7(2): 64-69.

[8] . The role of copper in neurodegenerative diseas[J]. Neurobiol. Dis., 1999, 6(4): 221-230.

[9] . Undetectable intracellular free copper: The requirement of a copper chaperone for superoxide dismutase[J]. Science, 1999, 284(5415): 805-808.

[10] . Solution and fluorescence properties of symmetric dipicolylamine-containing dichloro- fluorescein-based Zn2+ sensors[J]. J. Am. Chem. Soc., 2009, 131(20): 7142-7152.

[11] . Recognition preference of rhodamine-thiospirolactams for mercury(Ⅱ) in aqueous solution[J]. Inorg. Chem., 2009, 48(12): 5061-5072.

[12] Jana A, Kim J S, Jung H S, et al. A cryptand based chemodosimetric probe for naked-eye detection of mercury(II) ion in aqueous medium and its application in live cell imaging ［J］. Chem. Comm., 2009, (29):4417-4419.

[13] . Dansyl-based fluorescent chemosensors for selective responses of Cr(Ⅲ)[J]. New J. Chem., 2009, 33(3): 653-658.

[14] Wu H, He C, Wang J, et al. Hydrolysis-activated fluorophore system as a molecular sensor for selective detection of Zn2+ ［J］. Chin. J. Lumin.(发光学报), 2009, 30(3):275-283 (in Chinese).

[15] . A turn-on fluorescent sensor for detecting nickel in living cells[J]. J. Am. Chem. Soc., 2009, 131(50): 18020-18021.

[16] Li G K, Xu Z X, Chen C F. A highly efficient and selective turn-on fluorescent sensor for Cu2+ ion based on calix［4］arene bearing four iminoquinoline subunits on the upper rim ［J］. Chem. Comm., 2008, (28):1774-1776.

[17] Swamy K M K, Ko S K, Kwon S K, et al. Boronic acid-linked fluorescent and colorimetric probes for copper ions ［J］.Chem. Comm., 2008, (28):5915-5917.

[18] . Highly sensitive and fast responsive fluorescence turn-on chemodosimeter for Cu2+ and its application in live cell Imaging[J]. Chem. Eur. J., 2008, 14(23): 6892-6900.

[19] Wen Z C, Yang R, He H, et al. A highly selective charge transfer fluoroionophore for Cu2+ ［J］. Chem. Comm., 2006, (2):106-108.

[20] . Cu2+-selective ratiometric and “Off-On” sensor based on the rhodamine derivative bea-ring pyrene group[J]. Org. Lett., 2009, 11(19): 4442-4445.

[21] SMART SA INT, Area detector control and integration software, siemens analytical X-ray systems ［G］. Madison: Inc. Madison. WI, 1996.

[22] Sheldrick G M, SHELXTL V5.1, Software ReferenceManual, Bruker, AXS ［G］. Madison: Inc. Madison WI, 1997.

[23] . Synthesis and characterization of zinc sensors based on a monosubstituted fluorescein platform[J]. Inorg. Chem., 2004, 43(8): 2624-2635.

[24] . A DNAzyme catalytic beacon sensor for paramagnetic Cu2+ ions in aqueous solution with high sensitivity and selectivity[J]. J. Am. Chem. Soc., 2007, 129(32): 9838-9839.

[25] Jiang P, Guo Z. Fluorescent detection of zinc in biological systems: recent development on the design of chemosensors and biosensors ［J］. Coord. Chem. Rev., 2004, 248(1-2):205-229.

[26] . Fluorescent chemosensors for Cu2+ ions: Fast, selective, and highly sensitive[J]. Angew. Chem. Int. Ed., 1998, 37(6): 772-773.