光学学报, 2016, 36 (9): 0911002, 网络出版: 2016-09-09   

散射光声探测技术及其成像方法

Scattering Photoacoustic Detection Technique and Its Imaging Method
李琳 1,*唐志列 1,2,3吴泳波 1,2,3
作者单位
1 华南师范大学物理与电信工程学院, 广东 广州 510006
2 华南师范大学广东省量子调控工程与材料重点实验室, 广东 广州 510006
3 华南师范大学广东省光电检测仪器工程技术研究中心, 广东 广州 510006
摘要
为了实现强散射样品的光声显微成像,提出了一种散射光声显微成像新技术。利用散射光声效应原理,成功设计研制了散射光声探测器。散射光声探测器由散射光声腔、耦合腔、微通道以及微音器组成。利用该探测器探测样品的散射光声信号,然后结合共焦扫描成像技术实现了强散射样品的光声显微成像,获得了二氧化硅微球和口腔上皮细胞等各种不同散射样品的光声显微图像。实验结果表明,散射光声显微成像技术可以极大地改善图像对比度和增强图像边缘,对于工业、大气等方面的微粒直径测量具有重要的应用意义。
Abstract
In order to realize the photoacoustic microscopic imaging of strong scattering sample, a new method for scattering photoacoustic imaging is presented. A scattering photoacoustic detector is successfully designed by applying the scattering photoacoustic effect principle. The scattering photoacoustic detector consists of a scattering photoacoustic cavity, a resonant cavity, a microchannel and a microphone. The detector is used to detect photoacoustic signals of samples. Then, combining confocal scanning imaging technology, the photoacoustic microscopy imaging of strong scattering samples are achieved. Photoacoustic microscopic images of various kinds of scattering samples, such as silica microspheres and oral epithelial cells are successfully obtained as well. The results indicate that scattering photoacoustic imaging technique can greatly improve the image contrast and enhance image edge. This technique has important application meanings of particle diameters measurement in the field of industry and atmosphere.
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李琳, 唐志列, 吴泳波. 散射光声探测技术及其成像方法[J]. 光学学报, 2016, 36(9): 0911002. Li Lin, Tang Zhilie, Wu Yongbo. Scattering Photoacoustic Detection Technique and Its Imaging Method[J]. Acta Optica Sinica, 2016, 36(9): 0911002.

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