This paper provides a simple hybrid design and numerical analysis of the graphene-coated fiber-optic surface plasmon resonance (SPR) biosensor for breast cancer gene-1 early onset (BRCA1) and breast cancer gene-2 early onset (BRCA2) genetic breast cancer detection. Two specific mutations named 916delTT and 6174delT in the BRCA1 and BRCA2 are selected for numerical detection of breast cancer. This sensor is based on the technique of the attenuated total reflection (ATR) method to detect deoxyribonucleic acid (DNA) hybridization along with individual point mutations in BRCA1 and BRCA2 genes. We have numerically shown that momentous changes present in the SPR angle (minimum: 135 % more) and surface resonance frequency (SRF) (minimum: 136 % more) for probe DNA with various concentrations of target DNA corresponding to a mutation of the BRCA1 and BRCA2 genes. The variation of the SPR angle and SRF for mismatched DNA strands is quite negligible, whereas that for complementary DNA strands is considerable, which is essential for proper detection of genetic biomarkers (916delTT and 6174delT) for early breast cancer. At last, the effect of electric field distribution in inserting graphene layer is analyzed incorporating the finite difference time domain (FDTD) technique by using Lumerical FDTD solution commercial software. To the best of our knowledge, this is the first demonstration of such a highly efficient biosensor for detecting BRCA1 and BRCA2 breast cancer. Therefore, the proposed biosensor opens a new window toward the detection of breast cancers.

北京大学3.5-cell直流超导(DC-SRF)光阴极注入器需要一台连续波功率20 kW的1.3 GHz微波功率源。为此北京大学和北京北广科技股份有限公司联合研制了一台由88个放大模块组成的固态微波功率放大器, 这是国内首台L波段连续波大功率固态功率源。在简要介绍这台微波功率放大器设计的基础上, 主要描述其调试过程和重要参数检测并着重讨论了全反射问题。测试结果显示这台功率源的各项参数均达到设计指标, 在输出功率20 kW时的效率为34%, 增益大于85 dB；在整个功率输出范围其增益和相移的变化分别为1.6 dB和9.5°。目前这台功率源已在DC-SRF光阴极注入器调试运行中稳定工作超过2000 h。

为了标定扫描式棱镜太阳光谱仪的棱镜不同转动角度对应的中心波长和光谱带宽, 利用了一种棱镜扫描方法对太阳光谱仪的光谱响应函数进行测量。 该方法使用固定的单色光波长, 控制棱镜转动实现单色光的像在探测器位置扫描, 并通过坐标映射得到响应位置的光谱响应函数。 文中根据光谱响应函数的定义, 推导出棱镜扫描法与单色仪波长扫描方法波长定标原理上的等效性。 之后分别以532 nm固体激光器和632.8 nm氦氖激光器为光源, 使用棱镜扫描法测量太阳光谱仪对应波长位置的光谱响应函数, 并以单色仪波长扫描法实验作为对比。 实验结果表明, 对于扫描式棱镜太阳光谱仪, 棱镜扫描法测量的中心波长分别为531.86和632.67 nm, 其准确度优于单色仪波长扫描法测得的531.39和631.97 nm。 由于不受单色仪性能的限制, 前者测量的光谱带宽值也优于后者。 最后以汞灯为光源使用棱镜扫描法对太阳光谱仪进行了光谱定标实验, 实现了特征光谱定标法结合棱镜扫描法对中心波长及光谱带宽的标定。 该方法同样可以应用于扫描式光栅光谱仪以及单色仪的光谱定标。

：针对大气层外的太阳光谱辐照度监测，设计了一种星载小型宽光谱太阳光谱仪。光学系统应用改进的切尔尼-特纳光学结构，工作波长范围为600~1 200 nm(二级光谱)和1 200~2 400 nm(一级光谱)；一二级光谱使用二向色分光镜分离，并采用两片线阵探测器同时接收，实现全谱瞬态直读。整个光学结构的尺寸为80 mm×55 mm×20 mm。经过系统优化，全谱段子午方向像差低于6 μm。基于惠更斯点扩散函数(PSF)，仿真探测器像元的光谱响应函数(SRF)，结果表明光谱分辨率在600~1 200 nm波段优于2 nm，在1 200~2 400 nm波段优于4 nm。系统结构简单紧凑，稳定性高，适合用于空间太阳光谱辐照度的在轨监测。

Charged particle diagnostics is one of the required techniques for implosion areal density diagnostics at the SG-III facility. Several proton spectrometers are under development, and some preliminary areal density diagnostics have been carried out. The response of the key detector, CR39, to charged particles was investigated in detail. A new track profile simulation code based on a semi-empirical model was developed. The energy response of the CR39 detector was calibrated with the accelerator protons and alphas from a 241Am source. A proton spectrometer based on the filtered CR39 detector was developed, and D–D primary proton measurements were implemented. A step range filter spectrometer was developed, and preliminary areal density diagnostics was carried out. A wedged range filter spectrometer array made of Si with a higher resolution was designed and developed at the SG-III facility. A particle response simulation code by the Monte Carlo method and a spectra unfolding code were developed. The capability was evaluated in detail by simulations.

遥感数据模拟已广泛应用于遥感研究中, 遥感模拟对于新型传感器的设计, 新算法的检测等都有积极的意义。 然而传感器系统参数的变化会影响数据模拟的精度。 实验采用卷积宽视场多光谱成像仪蓝、 绿、 红和近红外四个波段的光谱响应函数, 基于光谱重构的方法对多光谱数据进行了高光谱的数据模拟。 研究分析了多光谱数据中心波长和带宽的变化对高光谱重构精度的影响。 结果表明, 中心波长和带宽的变化对于光谱重构精度有一定的影响, 但总体来说模拟结果有很好的精度。 中心波长的变化所引起的RMSE小于0.025, 带宽变化引起的RMSE小于0.012。 因而基于中心波长和带宽变化的高光谱数据重构有助于用户更好的了解高光谱成像系统, 找到系统性能的主要影响者, 以便更好的模拟高光谱数据, 扩展遥感数据的应用范围。