Chinese Optics Letters, 2020, 18 (12): 121705, Published Online: Dec. 8, 2020   

Deep learning virtual colorful lens-free on-chip microscopy Download: 796次

Hua Shen 1,2,3,*Jinming Gao 1,2
Author Affiliations
1 School of Electronic Engineering and Optoelectronic Technology, Nanjing University of Science and Technology, Nanjing 210094, China
2 MIIT Key Laboratory of Advanced Solid Laser, Nanjing University of Science and Technology, Nanjing 210094, China
3 Department of Material Science and Engineering, University of California Los Angeles, Los Angeles, CA 90095, USA
Figures & Tables

Fig. 1. Lens-free on-chip microscope setup. (a) Schematic of lens-free on-chip microscopy. (b) Experimental lens-free on-chip microscope setup. (c) An example image of H&E stained pathological tumor tissue.

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Fig. 2. Computational algorithm flowchart to get a virtually colorized lens-free on-chip microscopy image.

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Fig. 3. Deep learning GAN established to achieve virtual colorization.

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Fig. 4. Data processing to achieve virtual colorful lens-free on-chip microscopy. The yellow scale bar is 200 μm.

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Fig. 5. Comparisons of lens-free on-chip microscopy image, bench-top commercial microscopy image, and virtual colorization image, which are image pairs of ROIs #1, #2, and #3 in Fig. 4.

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Hua Shen, Jinming Gao. Deep learning virtual colorful lens-free on-chip microscopy[J]. Chinese Optics Letters, 2020, 18(12): 121705.

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