The diffuse reflectance of single-fiber reflectance probe is studied with the Monte Carlo simulation, and we find that the sub-diffuse scattering light is sensitive to the scattering phase function (SPF) related to tissue microstructure. A semi-empirical diffuse reflection model for small aperture measurement is studied, and the influences of second-order and third-order optic parameters on this model are analyzed. It shows that the two parameters have contrary effects on diffuse reflectance, and both effects are non-negligible for optically anisotropic biological tissues. A simplified semi-empirical model and its application condition are given, which provides potentially applicable support for measurement of tissue scattering properties and associated microstructure.
Fig. 3. (a) Variation of diffuse reflectance with detector aperture when g=0.65; (b) variation of diffuse reflectance with detector aperture when γ=1.5; (c) relative change of diffuse reflectance in Fig. 3(a) with reference to point B; (d) relative change of diffuse reflectance in Fig. 3(c) with reference to point E
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刘迎, 罗雯倩, 王汝丹, 王兴. 生物组织的亚扩散散射及其光谱技术的应用[J]. 中国激光, 2017, 44(8): 0807001. Liu Ying, Luo Wenqian, Wang Rudan, Wang Xing. Sub-Diffuse Scattering of Biological Tissues and Its Application to Spectroscopy[J]. Chinese Journal of Lasers, 2017, 44(8): 0807001.